In this video, I explain why I support the Life Extension Advocacy Foundation, and why I think you should too. You can help defeating age-related diseases by voting for LEAF in Project4Awesome 2017!
VOTE FOR THIS VIDEO: [link coming!]
LEAF's website: https://www.leafscience.org
LEAF's crowdfunding platform for aging research: https://lifespan.io
Hank's video on aging: https://www.youtube.com/watch?v=jqCo-McgHLw
Kurzgesagt's first video on aging: https://www.youtube.com/watch?v=GoJsr4IwCm4
Kurzgesagt's second video on aging: https://www.youtube.com/watch?v=MjdpR-TY6QU
The Hallmarks of Aging (open-access paper): http://www.cell.com/cell/fulltext/S0092-8674
LEAF's discussion of the Hallmarks: https://www.leafscience.org/aging/
Some studies showing the effect of damage repair on aging:
Baker, D. J., Wijshake, T., Tchkonia, T., LeBrasseur, N. K., Childs, B. G., Van De Sluis, B., … & Van Deursen, J. M. (2011). Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature, 479(7372), 232
Zhu, Y., Tchkonia, T., Pirtskhalava, T., Gower, A. C., Ding, H., Giorgadze, N., ... & O'hara, S. P. (2015). The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs. Aging cell, 14(4), 644-658.